Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-28-08 | Translational 2 | ETA2023

Understanding the putative role OF ACE2, TMPRSS2 and furin proteins on thyroid neoplastic transformation

Teresa Azevedo Maria , Macedo Sofia , Canberk Sule , Batista Rui , Soares Paula

Angiotensin-converting enzyme 2 (ACE2), Transmembrane serine protease 2 (TMPRSS2) and Furin were known to be key players for the SARS-CoV-2 infection. Thyroid gland was shown to be one of the relevant targets for SARS-CoV-2 infection allegedly due to the higher expression levels of these molecules in follicular cells. However, it remains to be fully determined the expression of ACE2, TMPRSS2 and Furin in normal follicular cell. In addition, the putative role of these molecules...